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Abstract

INTERNATIONAL JOURNAL OF CLINICAL INVESTIGATION AND CASE REPORTS - Volume 2, Issue 1, (Jan-Mar)

Pages: 1-5

Hematological Alterations Associated with COVID-19 Severe

Gabriel Macedo Costa Guimarães* (BRAZIL)

Category: Virology

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Abstract:

Since the onset of the COVID-19 pandemic in 2020, several studies have been relating the severity of the disease with hematological and coagulation changes besides a strong immune response. Understanding what these changes are, in addition to seeking predictive biomarkers of mortality, has become an essential task to help control and reduce the death rate during hospitalization of COVID-19 patients with a severe clinical conditions. The objective of this study was to evaluate the hematological alterations according to the clinical outcomes of COVID-19. Hematological alterations such as lymphopenia, leukocytosis, neutrophilia, and decrease in hemoglobin and red blood cells, in addition to a state of hypercoagulability and cytokine storm, have become the main alterations present in hospitalized patients with COVID-19. The initial identification of these abnormalities is useful for the early prognosis of individuals who may die during hospitalization and thus allow these patients to receive targeted support to improve their clinical condition.

Keywords: COVID-19, Hematological, Abnormalities, Lymphopenia, Neutrophilia

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DOI: 10.55828/ijcicr-21-01

DOI URL: http://dx.doi.org/10.55828/ijcicr-21-01