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      <JournalTitle>International Journal of Clinical Investigation and Case Reports</JournalTitle>
      <Volume-Issue>Volume 1, Issue 1</Volume-Issue>
      <ArticleTitle>Skene’s Gland Adenofibroma: A Diagnostic Challenge of a Rare Entity</ArticleTitle>
          <FirstName>Yahya Elshimali*</FirstName>
      <Abstract>Skene’s glands are a pair of female paraurethral glands with similar embryologic, physiologic, and pathologic features to the male prostate. Cysts and abscesses represent the most common pathological changes affecting Skene’s gland, whereas adenofibromas represent an extremely rare entity. Herein, we present a rare case report of adenofibroma in the Skene’s gland of a postmenopausal female.</Abstract>
      <Keywords>Skene’s Gland,Adenofibroma,Immunohistochemistry Staining</Keywords>
        <Abstract>https://ijcicr.com/ubijournal-v1copy/journals/abstract.php?article_id=13745&amp;title=Skene’s Gland Adenofibroma: A Diagnostic Challenge of a Rare Entity</Abstract>
        <References>Klein M. De Mulierum Organis Generationi Inservientibus (1672) of R. De Graaf. Le Scalpel. 1962; 115:109-13.&#13;
	Skene AJ. Anatomy and pathology of two important glands of the female urethra. Am J Obstet Dis Women Child. 1880; 13(2):265-270.&#13;
	Huffman JW. The detailed anatomy of the para-urethral ducts in the adult human female. Am J Obstet Gynecol. 1948; 55(1):86-101.&#13;
	Tregnago AC, Epstein JI. Skeneand;#39;s Glands Adenocarcinoma: A Series of 4 Cases. Am J Surg Pathol. 2018; 42(11):1513-1521.&#13;
	Saeed F, Osunkoya AO. Skene gland adenocarcinoma: Clinicopathologic features, comprehensive biomarker analysis, and review of the literature. Pathol Int. 2021; 71(10):712-714.&#13;
	Pollen JJ, Dreilinger A. Immunohistochemical identification of prostatic acid phosphatase and prostate specific antigen in female periurethral glands. Urology. 1984; 23(3):303-304.&#13;
	Tepper SL, Jagirdar J, Heath D, Geller SA. Homology between the female paraurethral (Skene’s) glands and the prostate. Immunohistochemical demonstration. Arch Pathol Lab Med. 1984; 108(5):423-425.&#13;
	Chong Y, Eom M, Park KH, Chung HC, Ro JY. Adenofibroma of Skeneand;#39;s Duct: A Case Report. Patholog Res Int. 2010; 2010:318973.&#13;
	Bettaieb I, Mekni A, Bellil K, et al. Endometrial adenofibroma: a rare entity. Archives of Gynecology and Obstetrics. 2007; 275(3):191-193.&#13;
	Wyckoff Facog ET, Cua GM, Lieberman L, Akki AS. The Skeneand;#39;s gland cyst that was not: an atypical presentation of a leiomyoma. J Obstet Gynaecol. 2020; 40(2):281-282.&#13;
	Lucioni A, Rapp D, Gong E, Fedunok P, Bales G. Diagnosis and management of periurethral cysts. Urologia Internationalis. 2007; 78(2):121-125.&#13;
	Kazakov DV, Stewart CJ, Kacerovska D, et al. Prostatic-type tissue in the lower female genital tract: a morphologic spectrum, including vaginal tubulosquamous polyp, adenomyomatous hyperplasia of paraurethral Skene glands (female prostate), and ectopic lesion in the vulva. Am J Surg Pathol. 2010; 34(7):950-955.&#13;
	Dwyer P. Skene’s gland revisited: function, dysfunction and the G spot. Int Urogynecology J. 2012; 23(2):135-137.</References>